Laboratory for Cell and Tissue Engineering

By combining materials engineering with cell biology and clinical research, the Ehrbar laboratory is engaged in studying and engineering tissue healing. Towards this end, we have developed materials, which by modular assembly of synthetic and biological building blocks allow creation of specific, cell-instructive, healing microenvironments. These platforms are being used to optimize materials properties and signals that control recruitment, expansion, and differentiation of local progenitor cells. Based on such findings next generation materials and application strategies are being designed, which will be tailored towards clinically relevant treatments.

We proudly announce the following recognitions:

  • Yannick Devaud receives the UZH Bio-Entrepreneur Fellowship Award 2018 for his project to close membrane defects after operative fetoscopic surgery
  • Ulrich Blache receives the ETH Medal for an outstanding PhD thesis
  • Queralt Vallmajo-Martin is the winner of the Best Poster Award of the 2018 Biointerfaces International Zurich conference
  • Ulrich Blache is the winner of the 2018 Research Award of the Swiss Society for Biomaterials and Regenerative Medicine
  • Queralt Vallmajo-Martin is the winner of the Travel Award of the Swiss Society for Biomaterials and Regenerative Medicine to participate in the 5th TERMIS World Congress 2018

Our Newest Publication

Extracellular Matrix Production by Mesenchymal Stromal Cells in Hydrogels Facilitates Cell Spreading and Is Inhibited by FGF‐2



Smart Hydrogels for the Augmentation of Bone Regeneration by Endogenous Mesenchymal Progenitor Cell Recruitment

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Expanded skeletal stem and progenitor cells promote and participate in
induced bone regeneration at subcritical BMP-2 dose

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Mesenchymal stromal cell activation by breast cancer
secretomes in bioengineered 3D microenvironments

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Article Notch-inducing hydrogels reveal a perivascular switch of mesenchymal stem cell fate

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Label-Free Quantification Proteomics for the Identification of Mesenchymal Stromal Cell Matrisome Inside 3D Poly(Ethylene Glycol) Hydrogels.

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